LOCUS       MG936619               16568 bp    DNA     circular PRI 26-MAR-2018
DEFINITION  Homo sapiens isolate TAF009.A0301 haplogroup U6a6b mitochondrion,
            complete genome.
ACCESSION   MG936619
VERSION     MG936619.1
DBLINK      BioProject: PRJNA422662
            BioSample: SAMN08193509
KEYWORDS    .
SOURCE      mitochondrion Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 16568)
  AUTHORS   van de Loosdrecht,M., Bouzouggar,A., Humphrey,L., Posth,C.,
            Barton,N., Aximu-Petri,A., Nickel,B., Nagel,S., Talbi,E.H., El
            Hajraoui,M.A., Amzazi,S., Hublin,J.J., Paabo,S., Schiffels,S.,
            Meyer,M., Haak,W., Jeong,C. and Krause,J.
  TITLE     Pleistocene North African genomes link Near Eastern and sub-Saharan
            African human populations
  JOURNAL   Science (2018) In press
   PUBMED   29545507
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16568)
  AUTHORS   van de Loosdrecht,M.S., Bouzouggar,A., Humphrey,L., Posth,C.,
            Barton,N., Aximu-Petri,A., Nickel,B., Nagel,S., Talbi,E.H., El
            Hajraoui,M.A., Amzazi,S., Hublin,J.-J., Paabo,S., Schiffels,S.,
            Meyer,M., Haak,W., Jeong,C. and Krause,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2018) Archaeogenetics, Max Planck Institute for
            the Science of Human History, Kahlaische Strasse 10, Jena 07745,
            Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Schmutzi v. 1.0
            Assembly Name         :: Complete mitogenome consensus sequences
                                     for 15,000y old North A
            Coverage              :: 102-1617x
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..16568
                     /organism="Homo sapiens"
                     /organelle="mitochondrion"
                     /mol_type="genomic DNA"
                     /isolate="TAF009.A0301"
                     /db_xref="taxon:9606"
                     /haplogroup="U6a6b"
                     /sex="male"
                     /tissue_type="petrous bone"
                     /dev_stage="infant"
                     /country="Morocco"
                     /note="Direct RC-date 14,805-13,908 cal. yBP"
     D-loop          complement(join(16028..16568,1..578))
     tRNA            578..648
                     /product="tRNA-Phe"
     rRNA            649..1602
                     /product="12S ribosomal RNA"
     tRNA            1603..1671
                     /product="tRNA-Val"
     rRNA            1672..3229
                     /product="16S ribosomal RNA"
     tRNA            3230..3304
                     /product="tRNA-Leu"
                     /note="codons recognized: UUR"
     gene            3307..4262
                     /gene="ND1"
     CDS             3307..4262
                     /gene="ND1"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:4261..4262,aa:TERM)
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 1"
                     /protein_id="AVP32575.1"
                     /translation="MPMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYG
                     LLQPFADAMKLFTKEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGL
                     LFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSF
                     NLSTLITTQEHLWLLLPSWPLAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAG
                     PFALFFMAEYTNIIMMNTLTTTIFLGTTYDALSPELYTTYFVTKTLLLTSLFLWIRTA
                     YPRFRYDQLMHLLWKNFLPLTLALLMWYVSMPITISSIPPQT"
     tRNA            4263..4331
                     /product="tRNA-Ile"
     tRNA            complement(4329..4400)
                     /product="tRNA-Gln"
     tRNA            4402..4469
                     /product="tRNA-Met"
     gene            4470..5511
                     /gene="ND2"
     CDS             4470..5511
                     /gene="ND2"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:5511,aa:TERM)
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 2"
                     /protein_id="AVP32576.1"
                     /translation="MNPLAQPVIYSTIFAGTLITALSSHWFFTWVGLEMNMLAFIPVL
                     TKKMNPRSTEAAIKYFLTQATASMILLMAILFNNMLSGQWTMTNTTNQYSSLMIMMAM
                     AMKLGMAPFHFWVPEVTQGTPLTSGLLLLTWQKLAPISIMYQISPSLNVSLLLTLSIL
                     SIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTAFLL
                     LNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWAIIEEFTKNNSL
                     IIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFLPTLIALTT
                     LLLPISPFMLMIL"
     tRNA            5512..5579
                     /product="tRNA-Trp"
     tRNA            complement(5587..5655)
                     /product="tRNA-Ala"
     tRNA            complement(5657..5729)
                     /product="tRNA-Asn"
     tRNA            complement(5761..5826)
                     /product="tRNA-Cys"
     tRNA            complement(5826..5891)
                     /product="tRNA-Tyr"
     gene            5904..7445
                     /gene="COX1"
     CDS             5904..7445
                     /gene="COX1"
                     /codon_start=1
                     /transl_table=2
                     /product="cytochrome c oxidase subunit I"
                     /protein_id="AVP32577.1"
                     /translation="MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQP
                     GNLLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSF
                     WLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILG
                     AINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTT
                     FFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWA
                     MMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKW
                     SAAVLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGG
                     FIHWFPLFSGYTLDQTYAKIHFTIMFIGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTW
                     NILSSVGSFISLTAVMLMIFMIWEAFASKRKVLMVEEPSMNLEWLYGCPPPYHTFEEP
                     VYMKS"
     tRNA            complement(7445..7516)
                     /product="tRNA-Ser"
                     /note="codons recognized: UCN"
     tRNA            7518..7585
                     /product="tRNA-Asp"
     gene            7586..8269
                     /gene="COX2"
     CDS             7586..8269
                     /gene="COX2"
                     /codon_start=1
                     /transl_table=2
                     /product="cytochrome c oxidase subunit II"
                     /protein_id="AVP32578.1"
                     /translation="MAHAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFL
                     TLTTKLTNTNISDAQEMETVWTILPAIILILIALPSLRILYMTDEVNDPSLTIKSIGH
                     QWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVL
                     HSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKI
                     FEMGPVFTL"
     tRNA            8295..8364
                     /product="tRNA-Lys"
     gene            8366..8572
                     /gene="ATP8"
     CDS             8366..8572
                     /gene="ATP8"
                     /codon_start=1
                     /transl_table=2
                     /product="ATP synthase F0 subunit 8"
                     /protein_id="AVP32579.1"
                     /translation="MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLPPSPKPMKM
                     KNYNKPWEPKWTKICSLHSFPPQS"
     gene            8527..9207
                     /gene="ATP6"
     CDS             8527..9207
                     /gene="ATP6"
                     /codon_start=1
                     /transl_table=2
                     /product="ATP synthase F0 subunit 6"
                     /protein_id="AVP32580.1"
                     /translation="MNENLFASFIPPTILGLPAAVLIILFPPLLIPTSKYLINNRLIT
                     TQQWLIKLTSKQMMTMHNTKGRTWSLMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNL
                     AMAIPLWAGAVIMGFRSKIKNALAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRL
                     TANITAGHLLMHLIGSATLAMSTINLPSTLIIFTILILLTILEIAVALIQAYVFTLLV
                     SLYLHDNT"
     gene            9207..9990
                     /gene="COX3"
     CDS             9207..9990
                     /gene="COX3"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:9990,aa:TERM)
                     /transl_table=2
                     /product="cytochrome c oxidase subunit III"
                     /protein_id="AVP32581.1"
                     /translation="MTHQSHAYHMVKPSPWPLTGALSALLMTSGLAMWFHFHSMTLLM
                     LGLLTNTLTMYQWWRDVTRESTYQGHHTPPVQKGLRYGMILFITSEVFFFAGFFWAFY
                     HSSLAPTPQLGGHWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMENNRNQMI
                     QALLITILLGLYFTLLQASEYFESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTIC
                     FIRQLMFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS"
     tRNA            9991..10058
                     /product="tRNA-Gly"
     gene            10059..10404
                     /gene="ND3"
     CDS             10059..10404
                     /gene="ND3"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:10404,aa:TERM)
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 3"
                     /protein_id="AVP32582.1"
                     /translation="MNFALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPM
                     SPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSL
                     AYEWLQKGLDWTE"
     tRNA            10405..10469
                     /product="tRNA-Arg"
     gene            10470..10766
                     /gene="ND4L"
     CDS             10470..10766
                     /gene="ND4L"
                     /codon_start=1
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 4L"
                     /protein_id="AVP32583.1"
                     /translation="MPLIYMNIMLAFTISLLGMLVYRSHLMSSLLCLEGMMLSLFIMA
                     TLMTLNTHSLLANIVPIAMLVFAACEAAVGLALLVSISNTYGLDYVHNLNLLQC"
     gene            10760..12137
                     /gene="ND4"
     CDS             10760..12137
                     /gene="ND4"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:12137,aa:TERM)
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 4"
                     /protein_id="AVP32584.1"
                     /translation="MLKLIVPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQ
                     INNNLFSCSPTFSSDPLTTPLLMLTTWLLPLTIMASQRHLSSEPLSRKKLYLSMLISL
                     QISLIMTFTATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPL
                     LIALIYTHNTLGSLNILLLTLTAQELSNSWANNLMWLAYTMAFMVKMPLYGLHLWLPK
                     AHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLVLSLWGMIMTSSIC
                     LRQTDLKSLIAYSSISHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNY
                     ERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTTFSWSNIT
                     LLLTGLNMLVTALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLN
                     PDIITGFSS"
     tRNA            12138..12206
                     /product="tRNA-His"
     tRNA            12207..12265
                     /product="tRNA-Ser"
                     /note="codons recognized: AGY"
     tRNA            12266..12336
                     /product="tRNA-Leu"
                     /note="codons recognized: CUN"
     gene            12337..14148
                     /gene="ND5"
     CDS             12337..14148
                     /gene="ND5"
                     /codon_start=1
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="AVP32585.1"
                     /translation="MTMHTTMTTLTLTSLIPPILTTLVNPNKKNSYPHYVKSIVASTF
                     IISLFPTTMFMCLDQEVIISNWHWATTQTTQLSLSFKLDYFSMMFIPVALFVTWSIME
                     FSLWYMNSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYA
                     RADANTAAIQAILYNRIGDIGFILALAWFILHSNSWDPQQMALLNANPSLTPLLGLLL
                     AAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPLAENSPLIQTL
                     TLCLGAITTLFAAVCALTQNDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICTHAF
                     FKAMLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTIGSLALAGMPFLTGFYSK
                     DHIIETANMSYTNAWALSITLIATSLTSAYSTRMILLTLTGQPRFPTLTNINENNPTL
                     LNPIKRLAAGSLFAGFLITNNISPASPFQTTIPLYLKLTALAVTFLGLLTALDLNYLT
                     NKLKMKSPLCTFYFSNMLGFYPSITHRTIPYLGLLTSQNLPLLLLDLTWLEKLLPKTI
                     SQHQISTSIITSTQKGMIKLYFLSFFFPLILTLLLIT"
     gene            complement(14149..14673)
                     /gene="ND6"
     CDS             complement(14149..14673)
                     /gene="ND6"
                     /codon_start=1
                     /transl_table=2
                     /product="NADH dehydrogenase subunit 6"
                     /protein_id="AVP32586.1"
                     /translation="MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIIL
                     NFGGGYMGLMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGL
                     VLWVKEYDGVVVVVNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGRWLVVVTGWTL
                     FVGVYIVIEIARGN"
     tRNA            complement(14674..14742)
                     /product="tRNA-Glu"
     gene            14747..15887
                     /gene="CYTB"
     CDS             14747..15887
                     /gene="CYTB"
                     /note="TAA stop codon is completed by the addition of 3' A
                     residues to the mRNA"
                     /codon_start=1
                     /transl_except=(pos:15887,aa:TERM)
                     /transl_table=2
                     /product="cytochrome b"
                     /protein_id="AVP32587.1"
                     /translation="MTPMRKINPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQ
                     ITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGL
                     YYGSFLYSETWNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDL
                     VQWIWGGYSVDSPTLTRFFTFHFILPFIIAALAALHLLFLHETGSNNPLGITSHSDKI
                     TFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLF
                     AYTILRSVPNKLGGVLALLLSILILAMIPILHMSKQQSMMFRPLSQSLYWLLAADLLI
                     LTWIGGQPVSYPFTIIGQVASVLYFTTILILMPTISLIENKMLKWA"
     tRNA            15888..15953
                     /product="tRNA-Thr"
     tRNA            complement(15955..16023)
                     /product="tRNA-Pro"
ORIGIN      
        1 gatcacaggt ctatcaccct attaaccact cacgggagct ctccatgcat ttggtatttt
       61 cgtctggggg gtgtgcacgc gatagcattg cgagacgctg gagccggagc accctatgtc
      121 gcagtatctg tctttgattc ctgcctcatc ctattattta tcgcacctac gttcaatatt
      181 acaggcgaac atacttacta aagtgtgtta attaattaat gcttgtagga cataataata
      241 acaattgaat gtctgcacag ccgctttcca cacagacatc ataacaaaaa atttccacca
      301 aaccccccct ccccccgctt ctggccacag cacttaaaca catctctgcc aaaccccaaa
      361 aacaaagaac cctaacacca gcctaaccag atttcaaatt ttatcttttg gcggtatgca
      421 cttttaacag tcacccccca actaacacat tattttcccc tcccactccc atactactaa
      481 tctcatcaat acaacccccg cccatcctac ccagcacaca cacaccgctg ctaaccccat
      541 accccgaacc aaccaaaccc caaagacacc ccccacagtt tatgtagctt acctcctcaa
      601 agcaatacac tgaaaatgtt tagacgggct cacatcaccc cataaacaaa taggtttggt
      661 cctagccttt ctattagctc ttagtaagat tacacatgca agcatccccg ttccagtgag
      721 ttcaccctct aaatcaccac gatcaaaagg gacaagcatc aagcacgcag caatgcagct
      781 caaaacgctt agcctagcca cacccccacg ggaaacagca gtgattaacc tttagcaata
      841 aacgaaagtt taactaagct atactaaccc cagggttggt caatttcgtg ccagccaccg
      901 cggtcacacg attaacccaa gtcaatagaa gccggcgtaa agagtgtttt agatcacccc
      961 ctccccaata aagctaaaac tcacctgagt tgtaaaaaac tccagttgac acaaaataga
     1021 ctacgaaagt ggctttaaca tatctgaaca cacaatagct aagacccaaa ctgggattag
     1081 ataccccact atgcttagcc ctaaacctca acagttaaat caacaaaact gctcgccaga
     1141 acactacgag ccacagctta aaactcaaag gacctggcgg tgcttcatat ccctctagag
     1201 gagcctgttc tgtaatcgat aaaccccgat caacctcacc acctcttgct cagcctatat
     1261 accgccatct tcagcaaacc ctgatgaagg ctacaaagta agcgcaagta cccacgtaaa
     1321 gacgttaggt caaggtgtag cccatgaggt ggcaagaaat gggctacatt ttctacccca
     1381 gaaaactacg atagccctta tgaaacttaa gggtcgaagg tggatttagc agtaaactga
     1441 gagtagagtg cttagttgaa cagggccctg aagcgcgtac acaccgcccg tcaccctcct
     1501 caagtatact tcaaaggaca tttaactaaa acccctacgc atttatatag aggagacaag
     1561 tcgtaacatg gtaagtgtac tggaaagtgc acttggacga accagagtgt agcttaacac
     1621 aaagcaccca acttacactt aggagatttc aacttaactt gaccgctctg agctaaacct
     1681 agccccaaac ccactccacc ttactaccag acaaccttag ccaaaccatt tacccaaata
     1741 aagtataggc gatagaaatt gaaacctggc gcaatagata tagtaccgca agggaaagat
     1801 gaaaaattat aaccaagcat aatatagcaa ggactaaccc ctataccttc tgcataatga
     1861 attaactaga aataactttg caaggagagc caaagctaag acccccgaaa ccagacgagc
     1921 tacctaagaa cagctaaaag agcacacccg tctatgtagc aaaatagtgg gaagatttat
     1981 aggtagaggc gacaaaccta ccgagcctgg tgatagctgg ttgtccaaga tagaatctta
     2041 gttcaacttt aaatttgccc acagaaccct ctaaatcccc ttgtaaattt aactgttagt
     2101 ccaaagagga acagctcttt ggacactagg aaaaaacctt gtagagagag taaaaaattt
     2161 aacacccata gtaggcctaa aagcagccac caattaagaa agcgttcaag ctcaacaccc
     2221 actacctaaa aaatcccaaa catataactg aactcctcac acccaattgg accaatctat
     2281 caccctatag aagaactaat gttagtataa gtaacatgaa aacattctcc tccgcataag
     2341 cctgcgtcag attaaaacac tgaactgaca attaacagcc caatatctac aatcaaccaa
     2401 caagtcatta ttaccctcac tgtcaaccca acacaggcat gctcataagg aaaggttaaa
     2461 aaaagtaaaa ggaactcggc aaatcttacc ccgcctgttt accaaaaaca tcacctctag
     2521 catcaccagt attagaggca ccgcctgccc agtgacacat gtttaacggc cgcggtaccc
     2581 taaccgtgca aaggtagcat aatcacttgt tccttaaata gggacctgta tgaatggctc
     2641 cacgagggtt cagctgtctc ttacttttaa ccagtgaaat tgacctgccc gtgaagaggc
     2701 gggcatgaca cagcaagacg agaagaccct atggagcttt aatttattaa tgcaaacagt
     2761 acctaacaaa cccacaggtc ctaaactacc aaacctgcat taaaaatttc ggttggggcg
     2821 acctcggagc agaacccaac ctccgagcag tacatgctaa gacttcacca gtcaaagcga
     2881 actactatac tcaattgatc caataacttg accaacggaa caagttaccc tagggataac
     2941 agcgcaatcc tattctagag tccatatcaa caatagggtt tacgacctcg atgttggatc
     3001 aggacatccc gatggtgcag ccgctattaa aggttcgttt gttcaacgat taaagtccta
     3061 cgtgatctga gttcagaccg gagtaatcca ggtcggtttc tatctacttc aaattcctcc
     3121 ctgtacgaaa ggacaagaga aataaggcct acttcacaaa gcgccttccc ccgtaaatga
     3181 tatcatctca acttagtatt atacccacac ccacccaaga acagggtttg ttaagatggc
     3241 agagcccggt aatcgcataa aacttaaaac tttacagtca gaggttcaat tcctcttctt
     3301 aacaacatac ccatggccaa cctcctactc ctcattgtac ccattctgat cgcaatggca
     3361 ttcctaatgc ttaccgaacg aaaaattcta ggctatatac aactacgcaa aggccccaac
     3421 gttgtaggcc cctacgggct actacaaccc ttcgctgacg ccataaaact cttcaccaaa
     3481 gagcccctaa aacccgccac atctaccatc accctctaca tcaccgcccc gaccttagct
     3541 ctcaccatcg ctcttctact atgaaccccc ctccccatac ccaaccccct ggtcaacctc
     3601 aacctaggcc tcctatttat tctagccacc tctagcctag ccgtttactc aatcctctga
     3661 tcagggtgag catcaaactc aaactacgcc ctgatcggcg cactgcgagc agtagcccaa
     3721 acaatctcat atgaagtcac cctagccatc attctactat caacattact aataagtggc
     3781 tcctttaacc tctccaccct tatcacaaca caagaacacc tctgattact cctgccatca
     3841 tgacccttgg ccataatatg atttatctcc acactagcag agaccaaccg aacccccttc
     3901 gaccttgccg aaggggagtc cgaactagtc tcaggcttca acatcgaata cgccgcaggc
     3961 cccttcgccc tattcttcat agccgaatac acaaacatta ttataataaa caccctcacc
     4021 actacaatct tcctaggaac aacatatgac gcactctccc ctgaactcta cacaacatat
     4081 tttgtcacca agaccctact tctaacctcc ctgttcttat gaattcgaac agcatacccc
     4141 cgattccgct acgaccaact catacacctc ctatgaaaaa acttcctacc actcacccta
     4201 gcattactta tatgatatgt ctccataccc attacaatct ccagcattcc ccctcaaacc
     4261 taagaaatat gtctgataaa agagttactt tgatagagta aataatagga gcttaaaccc
     4321 ccttatttct aggactatga gaatcgaacc catccctgag aatccaaaat tctccgtgcc
     4381 acctatcaca ccccatccta aagtaaggtc agctaaataa gctatcgggc ccataccccg
     4441 aaaatgttgg ttataccctt cccgtactaa ttaatcccct ggcccaaccc gtcatctact
     4501 ctaccatctt tgcaggcaca ctcatcacag cgctaagctc gcactgattt tttacctgag
     4561 taggcctaga aataaacatg ctagctttta ttccagttct aaccaaaaaa ataaaccctc
     4621 gttccacaga agctgccatc aagtatttcc tcacgcaagc aaccgcatcc ataatccttc
     4681 taatagctat cctcttcaac aatatactct ccggacaatg aaccataacc aatactacca
     4741 atcaatactc atcattaata atcataatgg ctatagcaat aaaactagga atagccccct
     4801 ttcacttctg agtcccagag gttacccaag gcacccctct gacatccggc ctgcttcttc
     4861 tcacatgaca aaaactagcc cccatctcaa tcatatacca aatctctccc tcactaaacg
     4921 taagccttct cctcactctc tcaatcttat ccatcatagc aggcagttga ggtggattaa
     4981 accaaaccca gctacgcaaa atcttagcat actcctcaat tacccacata ggatgaataa
     5041 tagcagttct accgtacaac cctaacataa ccattcttaa tttaactatt tatattatcc
     5101 taactactac cgcattccta ctactcaact taaactccag caccacgacc ctactactat
     5161 ctcgcacctg aaacaagcta acatgactaa cacccttaat tccatccacc ctcctctccc
     5221 taggaggcct gcccccgcta accggctttt tgcccaaatg ggccattatc gaagaattca
     5281 caaaaaacaa tagcctcatc atccccacca tcatagccac catcaccctc cttaacctct
     5341 acttctacct acgcctaatc tactccacct caatcacact actccccata tctaacaacg
     5401 taaaaataaa atgacagttt gaacatacaa aacccacccc attcctcccc acactcatcg
     5461 cccttaccac gctactccta cctatctccc cttttatact aataatctta tagaaattta
     5521 ggttaaatac agaccaagag ccttcaaagc cctcagtaag ttgcaatact taatttctgt
     5581 aacagctaag gactgcaaaa ccccactctg catcaactga acgcaaatca gccactttaa
     5641 ttaagctaag cccttactag accaatggga cttaaaccca caaacactta gttaacagct
     5701 aagcacccta atcaactggc ttcaatctac ttctcccgcc gccgggaaaa aaggcgggag
     5761 aagccccggc aggtttgaag ctgcttcttc gaatttgcaa ttcaatatga aaatcacctc
     5821 ggagctggta aaaagaggcc taacccctgt ctttagattt acagtccaat gcttcactca
     5881 gccattttac ctcaccccca ctgatgttcg ccgaccgttg actattctct acaaaccaca
     5941 aagacattgg aacactatac ctattattcg gcgcatgagc tggagtccta ggcacagctc
     6001 taagcctcct tattcgagcc gagctgggcc agccaggcaa ccttctaggt aacgaccaca
     6061 tctacaacgt tatcgtcaca gcccatgcat ttgtaataat cttcttcata gtaataccca
     6121 tcataatcgg aggctttggc aactgactag ttcccctaat aatcggtgcc cccgatatgg
     6181 cgtttccccg cataaacaac ataagcttct gactcttacc tccctctctc ctactcctgc
     6241 tcgcatctgc tatagtggag gccggagcag gaacaggttg aacagtctac cctcccttag
     6301 cagggaacta ctcccaccct ggagcctccg tagacctaac catcttctcc ttacacctag
     6361 caggtgtctc ctctatctta ggggccatca atttcatcac aacaattatc aatataaaac
     6421 cccctgccat aacccaatac caaacgcccc tcttcgtctg atccgtccta atcacagcag
     6481 tcctacttct cctatctctc ccagtcctag ctgctggcat cactatacta ctaacagacc
     6541 gcaacctcaa caccaccttc ttcgaccccg ccggaggagg agaccccatt ctataccaac
     6601 acctattctg atttttcggt caccctgaag tttatattct tatcctacca ggcttcggaa
     6661 taatctccca tattgtaact tactactccg gaaaaaaaga accatttgga tacataggta
     6721 tggtctgagc tatgatatca attggcttcc tagggtttat cgtgtgagca caccatatat
     6781 ttacagtagg aatagacgta gacacacgag catatttcac ctccgctacc ataatcatcg
     6841 ctatccccac cggcgtcaaa gtatttagct gactcgccac actccacgga agcaatatga
     6901 aatgatctgc tgcagtgctc tgagccctag gattcatctt tcttttcacc gtaggtggcc
     6961 tgactggcat tgtattagca aactcatcac tagacatcgt actacacgac acgtactacg
     7021 ttgtagctca cttccactat gtcctatcaa taggagctgt atttgccatc ataggaggct
     7081 tcattcactg atttccccta ttctcaggct acaccctaga ccaaacctac gccaaaatcc
     7141 atttcactat catattcatc ggcgtaaatc taactttctt cccacaacac tttctcggcc
     7201 tatccggaat gccccgacgt tactcggact accccgatgc atacaccaca tgaaacatcc
     7261 tatcatctgt aggctcattc atttctctaa cagcagtaat attaataatt ttcatgattt
     7321 gagaagcctt cgcttcgaag cgaaaagtcc taatagtaga agaaccctcc ataaacctgg
     7381 agtgactata tggatgcccc ccaccctacc acacattcga agaacccgta tacataaaat
     7441 ctagacaaaa aaggaaggaa tcgaaccccc caaagctggt ttcaagccaa ccccatggcc
     7501 tccatgactt tttcaaaaag gtattagaaa aaccatttca taactttgtc aaagttaaat
     7561 tataggctaa atcctatata tcttaatggc acatgcagcg caagtaggtc tacaagacgc
     7621 tacttcccct atcatagaag agcttatcac ctttcatgat cacgccctca taatcatttt
     7681 ccttatctgc ttcctagtcc tgtatgccct tttcctaaca ctcacaacaa aactaactaa
     7741 tactaacatc tcagacgctc aggaaataga aaccgtctga actatcctgc ccgccatcat
     7801 cctaatcctc atcgccctcc catccctacg catcctttac ataacagacg aggtcaacga
     7861 tccctccctt accatcaaat caattggcca ccaatggtac tgaacctacg agtacaccga
     7921 ctacggcgga ctaatcttca actcctacat acttccccca ttattcctag aaccaggcga
     7981 cctgcgactc cttgacgttg acaatcgagt agtactcccg attgaagccc ccattcgtat
     8041 aataattaca tcacaagacg tcttgcactc atgagctgtc cccacattag gcttaaaaac
     8101 agatgcaatt cccggacgtc taaaccaaac cactttcacc gctacacgac cgggggtata
     8161 ctacggtcaa tgctctgaaa tctgtggagc aaaccacagt ttcatgccca tcgtcctaga
     8221 attaattccc ctaaaaatct ttgaaatagg gcccgtattt accctatagc accccctcta
     8281 ccccctctag agcccactgt aaagctaact tagcattaac cttttaagtt aaagattaag
     8341 agaaccaaca cctctttaca gtgaaatgcc ccaactaaat actaccgtat ggcccaccat
     8401 aattacaccc atactcctta cactattcct catcacccaa ctaaaaatat taaacacaaa
     8461 ctaccaccta cctccctcac caaagcccat aaaaataaaa aattataaca aaccctgaga
     8521 accaaaatga acgaaaatct gttcgcttca ttcattcccc ccacaatcct aggcctaccc
     8581 gccgcagtac tgatcattct atttccccct ctattgatcc ccacctccaa atatctcatc
     8641 aacaaccgac taatcaccac ccaacaatga ctaatcaaac taacctcaaa acaaatgata
     8701 accatacaca acactaaagg acgaacctga tctcttatac tagtatcctt aatcattttt
     8761 attgccacaa ctaacctcct cggactcctg cctcactcat ttacaccaac cacccaacta
     8821 tctataaacc tagccatggc catcccctta tgagcgggcg cagtgattat aggctttcgc
     8881 tctaagatta aaaatgccct agcccacttc ttaccacaag gcacacctac accccttatc
     8941 cccatactag ttattatcga aaccatcagc ctactcattc aaccaatagc cctggccgta
     9001 cgcctaaccg ctaacattac tgcaggccac ctactcatgc acctaattgg aagcgccacc
     9061 ctagcaatat caaccattaa ccttccctct acacttatca tcttcacaat tctaattcta
     9121 ctgactatcc tagaaatcgc tgtcgcctta atccaagcct acgttttcac acttctagta
     9181 agcctctacc tgcacgacaa cacataatga cccaccaatc acatgcctat catatagtaa
     9241 aacccagccc atgaccccta acaggggccc tctcagccct cctaatgacc tccggcctag
     9301 ccatgtgatt tcacttccac tccataacgc tcctcatact aggcctacta accaacacac
     9361 taaccatata ccaatgatgg cgcgatgtaa cacgagaaag cacataccaa ggccaccaca
     9421 caccacctgt ccaaaaaggc cttcgatacg ggataatcct atttattacc tcagaagttt
     9481 ttttcttcgc aggatttttc tgagcctttt accactccag cctagcccct accccccaat
     9541 taggagggca ctggccccca acaggcatca ccccgctaaa tcccctagaa gtcccactcc
     9601 taaacacatc cgtattactc gcatcaggag tatcaatcac ctgagctcac catagtctaa
     9661 tagaaaacaa ccgaaaccaa ataattcaag cactgcttat tacaatttta ctgggtctct
     9721 attttaccct cctacaagcc tcagagtact tcgagtctcc cttcaccatt tccgacggca
     9781 tctacggctc aacatttttt gtagccacag gcttccacgg acttcacgtc attattggct
     9841 caactttcct cactatctgc ttcatccgcc aactaatatt tcactttaca tccaaacatc
     9901 actttggctt cgaagccgcc gcctgatact ggcattttgt agatgtggtt tgactatttc
     9961 tgtatgtctc catctattga tgagggtctt actcttttag tataaatagt accgttaact
    10021 tccaattaac tagttttgac aacattcaaa aaagagtaat aaacttcgcc ttaattttaa
    10081 taatcaacac cctcctagcc ttactactaa taattattac attttgacta ccacaactca
    10141 acggctacat agaaaaatcc accccttacg agtgcggctt cgaccctata tcccccgccc
    10201 gcgtcccttt ctccataaaa ttcttcttag tagctattac cttcttatta tttgatctag
    10261 aaattgccct ccttttaccc ctaccatgag ccctacaaac aactaacctg ccactaatag
    10321 ttatgtcatc cctcttatta atcatcatcc tagccctaag tctggcctat gagtgactac
    10381 aaaaaggatt agactgaacc gaattggtat atagtttaaa caaaacgaat gatttcgact
    10441 cattaaatta tgataatcat atttaccaaa tgcccctcat ttacataaat attatactag
    10501 catttaccat ctcacttcta ggaatactag tatatcgctc acacctcata tcctccctac
    10561 tatgcctaga aggaataata ctatcgctgt tcattatagc tactctcata accctcaaca
    10621 cccactccct cttagccaat attgtgccta ttgccatact agtctttgcc gcctgcgaag
    10681 cagcggtggg cctagcccta ctagtctcaa tctccaacac atatggccta gactacgtac
    10741 ataacctaaa cctactccaa tgctaaaact aatcgtccca acaattatat tactaccact
    10801 gacatgactt tccaaaaaac acataatttg aatcaacaca accacccaca gcctaattat
    10861 tagcatcatc cctctactat tttttaacca aatcaacaac aacctattta gctgttcccc
    10921 aaccttttcc tccgaccccc taacaacccc cctcctaata ctaactacct gactcctacc
    10981 cctcacaatc atggcaagcc aacgccactt atccagtgaa ccactatcac gaaaaaaact
    11041 ctacctctct atactaatct ccctacaaat ctccttaatt ataacattca cagccacaga
    11101 actaatcata ttttatatct tcttcgaaac cacacttatc cccaccttgg ctatcatcac
    11161 ccgatgaggc aaccagccag aacgcctgaa cgcaggcaca tacttcctat tctacaccct
    11221 agtaggctcc cttcccctac tcatcgcact aatttacact cacaacaccc taggctcact
    11281 aaacattcta ctactcactc tcactgccca agaactatca aactcctgag ccaacaactt
    11341 aatatgacta gcttacacaa tagcttttat agtaaagata cctctttacg gactccactt
    11401 atgactccct aaagcccatg tcgaagcccc catcgctggg tcaatagtac ttgccgcagt
    11461 actcttgaaa ctaggcggct atggtataat acgcctcaca ctcattctca accccctgac
    11521 aaaacacata gcctacccct tccttgtact atccctatga ggcataatta taacaagctc
    11581 catctgccta cgacaaacag acctaaaatc gctcattgca tactcttcaa tcagccacat
    11641 agccctcgta gtaacagcca ttctcatcca aaccccctga agcttcaccg gcgcagtcat
    11701 tctcataatc gcccacggac ttacatcctc attactattc tgcctagcaa actcaaacta
    11761 cgaacgcact cacagtcgca tcataatcct ctctcaagga cttcaaactc tactcccact
    11821 aatagctttt tgatgacttc tagcaagcct cgctaacctc gccttacccc ccactattaa
    11881 cctactggga gaactctctg tgctagtaac cacgttctcc tgatcaaata tcactctcct
    11941 acttacagga ctcaacatac tagtcacagc cctatactcc ctctacatat ttaccacaac
    12001 acaatggggc tcactcaccc accacattaa caacataaaa ccctcattca cacgagaaaa
    12061 caccctcatg ttcatacacc tatcccccat tctcctccta tccctcaacc ccgacatcat
    12121 taccgggttt tcctcttgta aatatagttt aaccaaaaca tcagattgtg aatctgacaa
    12181 cagaggctta cgacccctta tttaccgaga aagctcacaa gaactgctaa ctcatgcccc
    12241 catgtctaac aacatggctt tctcaacttt taaaggataa cagctatcca ttggtcttag
    12301 gccccaagaa ttttggtgca actccaaata aaagtaataa ccatgcacac tactataacc
    12361 accctaaccc taacttccct aattcccccc atccttacca ccctcgttaa ccctaacaaa
    12421 aaaaactcat acccccatta tgtaaaatcc attgtcgcat ccacctttat tatcagtctc
    12481 ttccccacaa caatattcat gtgcctagac caagaagtta ttatctcgaa ctgacactga
    12541 gccacaaccc aaacaaccca gctctcccta agcttcaaac tagactactt ctccataata
    12601 ttcatccctg tagcattgtt cgttacatgg tccatcatag aattctcact gtgatatata
    12661 aactcagacc caaacattaa tcagttcttc aaatatctac tcatcttcct aattaccata
    12721 ctaatcttag ttaccgctaa caacctattc caactgttca tcggctgaga gggcgtagga
    12781 attatatcct tcttgctcat cagttgatga tacgcccgag cagatgccaa cacagcagcc
    12841 attcaagcaa tcctatacaa ccgtatcggc gatatcggtt tcatcctcgc cttagcatga
    12901 tttatcctac actccaactc atgagaccca caacaaatag cccttctaaa cgctaatcca
    12961 agcctcaccc cactactagg cctcctccta gcagcagcag gcaaatcagc ccaattaggt
    13021 ctccacccct gactcccctc agccatagaa ggccccaccc cagtctcagc cctactccac
    13081 tcaagcacta tagttgtagc aggaatcttc ttactcatcc gcttccaccc cctagcagaa
    13141 aatagcccac taatccaaac tctaacacta tgcttaggcg ctatcaccac tctgttcgca
    13201 gcagtctgcg cccttacaca aaatgacatc aaaaaaatcg tagccttctc cacttcaagt
    13261 caactaggac tcataatagt tacaatcggc atcaaccaac cacacctagc attcctgcac
    13321 atctgtaccc acgccttctt caaagccata ctatttatgt gctccgggtc catcatccac
    13381 aaccttaaca atgaacaaga tattcgaaaa ataggaggac tactcaaaac catacctctt
    13441 acttcaacct ccctcaccat tggcagccta gcattagcag gaataccttt cctcacaggt
    13501 ttctactcca aagaccacat catcgaaacc gcaaacatat catacacaaa cgcctgagcc
    13561 ctatctatta ctctcatcgc tacctccctg acaagcgcct atagcactcg aataattctt
    13621 ctcaccctaa caggtcaacc tcgcttcccc acccttacta acattaacga aaataacccc
    13681 accctactaa accccattaa acgcctggca gccggaagcc tattcgcagg atttctcatt
    13741 actaacaaca tttcccccgc atcccccttc caaacaacaa tccccctcta cctaaaactc
    13801 acagccctcg ctgtcacttt cctaggactt ctaacagccc tagacctcaa ctacctaacc
    13861 aacaaactta aaataaaatc cccactatgc acattttatt tctccaacat actcggattc
    13921 taccctagca tcacacaccg cacaatcccc tatctaggcc ttcttacgag ccaaaacctg
    13981 cccctactcc tcctagacct aacctgacta gaaaagctat tacctaaaac aatttcacag
    14041 caccaaatct ccacctccat catcacctca acccaaaaag gcataattaa actttacttc
    14101 ctctctttct tcttcccact catcctaacc ctactcctaa tcacataacc tattcccccg
    14161 agcaatctca attacaatgt atacaccaac aaacaatgtt caaccagtaa ctactactaa
    14221 tcaacgccca taatcataca aagcccccgc accaatagga tcctcccgaa tcaaccctga
    14281 cccctctcct tcataaatta ttcagcttcc tacactatta aagtttacca caaccaccac
    14341 cccatcatac tctttcaccc acagcaccaa tcctacctcc atcgctaacc ccactaaaac
    14401 actcaccaag acctcaaccc ctgaccccca tgcctcagga tactcctcaa tagccatcgc
    14461 tgtagtatat ccaaagacaa ccatcattcc ccctaaataa attaaaaaaa ctattaaacc
    14521 catataacct cccccaaaat tcagaataat aacacacccg accacaccgc taacaatcaa
    14581 tactaaaccc ccataaatag gagaaggctt agaagaaaac cccacaaacc ccattactaa
    14641 acccacactc aacagaaaca aagcatacat cattattctc gcacggacta caaccacgac
    14701 caatgatatg aaaaaccatc gttgtatttc aactacaaga acaccaatga ccccaatacg
    14761 caaaattaac cccctaataa aattaattaa ccactcattc atcgacctcc ccaccccatc
    14821 caacatctcc gcatgatgaa acttcggctc actccttggc gcctgcctga tcctccaaat
    14881 caccacagga ctattcctag ccatgcacta ctcaccagac gcctcaaccg ccttttcatc
    14941 aatcgcccac atcactcgag acgtaaatta tggctgaatc atccgctacc ttcacgccaa
    15001 tggcgcctca atattcttta tctgcctctt cctacacatc gggcgaggcc tatattacgg
    15061 atcatttctc tactcagaaa cctgaaacat cggcattatc ctcctgcttg caactatagc
    15121 aacagccttc ataggctatg tcctcccgtg aggccaaata tcattctgag gggccacagt
    15181 aattacaaac ttactatccg ccatcccata cattgggaca gacctagttc aatgaatctg
    15241 aggaggctac tcagtagaca gtcccaccct cacacgattc tttacctttc acttcatctt
    15301 gcccttcatt attgcagccc tagcagcact ccacctccta ttcttgcacg aaacgggatc
    15361 aaacaacccc ctaggaatca cctcccattc cgataaaatc accttccacc cttactacac
    15421 aatcaaagac gccctcggct tacttctctt ccttctctcc ttaatgacat taacactatt
    15481 ctcaccagac ctcctaggcg acccagacaa ttatacccta gccaacccct taaacacccc
    15541 tccccacatc aagcccgaat gatatttcct attcgcctac acaattctcc gatccgtccc
    15601 taacaaacta ggaggcgtcc ttgccctatt actatccatc ctcatcctag caataatccc
    15661 catcctccat atatccaaac aacaaagcat aatatttcgc ccactaagcc aatcacttta
    15721 ttgactccta gccgcagacc tcctcattct aacctgaatc ggaggacaac cagtaagcta
    15781 cccctttacc atcattggac aagtagcatc cgtactatac ttcacaacaa tcctaatcct
    15841 aataccaact atctccctaa ttgaaaacaa aatactcaaa tgggcctgtc cttgtagtat
    15901 aaactaatac accagtcttg taaaccggag atgaaaacct ttttccaagg acaaatcaga
    15961 gaaaaagtct ttaactccac cattagcacc caaagctaag attctaattt aaactattct
    16021 ctgttctttc atggggaagc agatttgggt accacccaag tattgactca cccatcaaca
    16081 accgctatgt atttcgtaca ttactgccag ccaccatgaa tattgtacgg taccataaat
    16141 acttgaccac ctgtagtaca taaaaaccca acccacatca aaaccccctc cccatgctta
    16201 caagcaagta cagcaatcga ccctcaacta tcacacatca actgcaactc caaagccacc
    16261 cctcacccac taggatatca acaaacctac ccacccttaa cagtacatag tacataaagc
    16321 catttaccgt acatagcaca ttacagtcaa atcccttctc gtccccatgg atgacccccc
    16381 tcagataggg gtcccttgac caccatcctc cgtgaaatca atatcccgca caagagtgct
    16441 actctcctcg ctccgggccc ataacacttg ggggtagcta aagtgaactg tatccgacat
    16501 ctggttccta cttcagggtc ataaagccta aatagcccac acgttcccct taaataagac
    16561 atcacgat
//
